Low mortality and morbidity of upper gastrointestinal bleeding in Crete. The role of individual non steroidal anti-inflammatory drugs (NSAIDs)
نویسندگان
چکیده
Results: The median age of the patients was 62 and the male to female ratio 1.4: 1. In 64.2% of the cases a gastroduodenal ulcer was found. There was a history of NSAID use in 60.6% of patients and NSAID administration was associated significantly with antral erosions (81.7%). Operation and mortality rate were 3.6% and 2.7% respectively. Taking into account the local drug circulation, salicylates, piroxicam and ibuprofen were estimated to have the highest relative risk of bleeding. Drugs used mostly in parenteral or rectal forms were considered safer. No significant association was found between NSAID consumption and age, sex, operation and mortality rate.
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